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CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE

About

CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE belongs to a class of medication called 'cough and cold preparations' primarily used to treat dry cough. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs, namely: dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear the airways. 

CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE is a combination of three drugs, namely: Chlorpheniramine maleate (antihistamine), Phenylephrine hydrochloride (decongestant), and Dextromethorphan hydrobromide (cough suppressant). Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine hydrochloride helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Together, it helps to provide relief from dry cough.

Take CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE as prescribed. Your doctor will recommend how often you need to take CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE based on your medical condition. Some people may experience dry mouth, throat, or nose, drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects of CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before using CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE. Avoid using CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE if you have taken monoamine oxidase inhibitors in the past 14 days. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE. 

Uses of CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE

Dry cough

Medicinal Benefits

CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE is a combination of three drugs, namely: Chlorpheniramine maleate, Phenylephrine hydrochloride, and Dextromethorphan hydrobromide. CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE is a combination medicine belonging to a class of drugs called 'cough and cold preparations' primarily used to treat dry cough. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion or stiffness. Phenylephrine hydrochloride is a decongestant that helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE helps to relieve cough, cold and allergic symptoms.

Directions for Use

Syrup: Check the label for directions before using it. Shake the bottle well before use. Take CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE as prescribed by your doctor with the help of a measuring cup provided with the pack. Capsule/Tablet: Swallow it with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE

  • Dry mouth, throat or nose
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Headache
  • Constipation
  • Restlessness or excitation
  • Loss of appetite

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE. CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE is not recommended for children below 12 years of age. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE. Avoid taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE.

Drug Interactions

Drug-Drug Interaction: CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE may have interaction with anti-allergic drugs (diphenhydramine), anti-psychotic (escitalopram, desvenlafaxine, vilazodone), pain killer (aspirin), cold medicines (acetaminophen), antibiotics (amoxicillin), anti-depressants (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), beta-blockers (metoprolol, atenolol), muscle relaxants (carisoprodol, cyclobenzaprine).

Drug-Food Interaction: CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE may interact with alcohol. Therefore, avoid alcohol consumption with CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty in concentrating.

Drug-Disease Interaction: CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE may have interactions with disease conditions such as liver or kidney disease, asthma, diabetes, glaucoma, cardiovascular diseases, enlarged prostate, chronic bronchitis or emphysema (a lung condition causing shortness of breath).

Drug-Drug Interactions Checker List:

  • DIPHENHYDRAMINE
  • ESCITALOPRAM
  • DESVENLAFAXINE
  • VILAZODONE
  • ASPIRIN
  • ACETAMINOPHEN
  • AMOXICILLIN
  • LINEZOLID
  • PHENELZINE
  • SELEGILINE
  • RASAGILINE
  • ISOCARBOXAZID
  • TRANYLCYPROMINE
  • METOPROLOL
  • ATENOLOL
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consumption of alcohol with CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE as it may increase drowsiness. Please consult a doctor before consuming alcohol with CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE.

    • Safety Warning

      Pregnancy

      caution

      The safety of CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE in pregnant women is unknown. Consult your doctor if you have any concerns; your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE is excreted in human milk. Consult your doctor if you have any concerns; your doctor will decide if CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE.

    • Safety Warning

      Liver

      caution

      Take CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE with caution, especially if you have a history of liver disease. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE with caution, especially if you have a history of kidney disease. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      caution

      CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE is not recommended for children below 12 years of age. However, please consult a doctor before using CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE in children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods. 
    • Drink plenty of fluids to avoid a dry throat while you have a cough. It also helps loosen mucus.
    • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

    Special Advise

    • Talk to your doctor if your symptoms do not improve even after taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE for 7 days.
    • Contact a doctor immediately if you develop fever, rash or headaches after taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE. 

    Patients Concern

    Disease/Condition Glossary

    Cough: Coughing is a body's way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus and other matter) from the lungs, whereas, a dry cough doesn't produce sputum. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an infection in the respiratory tract. 

    FAQs

    CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE contains Chlorpheniramine maleate, Phenylephrine hydrochloride, and Dextromethorphan hydrobromide. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine hydrochloride helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. Dextromethorphan hydrobromide works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough.

    Consult your doctor before taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anaesthesia. Your doctor may advise you to stop taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE 72 hours prior to the surgery.

    It is not recommended to take CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or drug interaction. Also, CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE should be taken at least 14days after your last dose of anti-depressants.

    Take the missed dose as soon as you remember. However, if it is almost time for your next dose, wait until then to take CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE and skip the missed dose. Do not take extra medicine to make up for the missed dose.

    CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE may rarely worsen the symptoms of glaucoma. Therefore, CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE should be used with caution and only when prescribed by a doctor in patients with glaucoma.

    Available Medicines for

    CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+PHENYLEPHRINE HYDROCHLORIDE

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